
Marc Aurel Busche, M.D., Ph.D.
Principal Investigator, UK Dementia Research Institute, University College London
Honorary Consultant Psychiatrist, QueenSquare National Hospital for Neurology and Neurosurgery
Education
EMBO Long-Term Fellow, Massachusetts General Hospital & Harvard Medical School.
Clinical Residency in Psychiatry, University Hospital Klinikum Rechts der Isar, Munich.
Postdoctoral Researcher, Institute of Neuroscience, Munich.
M.D./Ph.D., Medical Life Sciences and Technology, Technical University of Munich.
Awards
UKRI Future Leaders Fellowship
AD/PD Junior Faculty Award
Kurt Kaufmann Prize
GSK Award for Clinical Research
EMPIRIS Award, Felgenhauer Award
Hans Jörg Weitbrecht Prize
Hans Heimann Prize

Previous Employment
Locum editor/editor, Biomed Central (Springer Nature), London.
Senior Postdoctoral Research Associate, Department of Psychology, University of Sheffield.
Postdoctoral Research Associate (secondment), Health Economics and Decision Science, School of Health and Related Research , University of Sheffield.
Joint postdoctoral position, Department of Psychology, University of Sheffield & Department of Neurological Surgery, Weill Cornell Medical College of Cornell University, New York Presbyterian Hospital, USA.
Clinical Autonomic Scientist, National Hospital for Neurology and Neurosurgery, UCLH.
Education
Ph.D. Neuroscience, University of Sheffield.
MSc Medical Physics, University of Surrey.
BSc Physics with Astronomy, University of Southampton.
Awards
Co-investigator on Eisai / UK DRI Research Programme on Dementia grant entitled: ‘Longitudinal monitoring of neurovascular dynamics in models of neurodegeneration’.
Co-investigator on MRC – KHIDI UK-Korea Partnering Award entitled: ‘Integrating multimodal imaging technologies to investigate neurovascular dysfunction in neurological disorders’.
Co-investigator on Epilepsy Research UK project entitled: ‘How activation of sensory regions can promote propagation of adjacent focal neocortical seizures’.
Exceptional Contribution Award for sustained research excellence (University of Sheffield).
Exceptional Contribution Award for research excellence (University of Sheffield).
Engineering and Physical Sciences Research Council ‘Pathways to Impact’ bursary for Science Communication.
Gold CREST (CREativity in Science and Technology) Award from the British Science Association.
Current Work in Our Lab
In addition to being involved in all aspects of the day to day management of the laboratory and staff training, I am also engaged in research examining neurovascular circuit dynamics in translational models of neuro-degenerative diseases, through the development and application of cutting-edge multi-modal imaging and electrophysiological techniques.

Previous Positions
Postdoctoral Researcher, INSERM Institute of Psychiatry and Neuroscience of Paris.
Joint Research Fellow, MRC Centre for Regenerative Medicine, University of Edinburgh and University of Strathclyde
Education
Ph.D. Regenerative Medicine, MRC Centre for Regenerative Medicine, University of Edinburgh.
MA Natural Sciences, University of Cambridge.
Awards
UK DRI Pilot Studies Programme Award 2020
Association CADASIL France Prize 2018
Current Work in Our Lab
My work looks at the contribution of non-neuronal cell types to Alzheimer’s Disease and dementia, with a focus on oligodendrocytes and the vasculature. This work involves studying these cells in vitro and in vivo to test hypotheses generated using single cell RNA sequencing of human tissue.

Education
Ph.D. Developmental Neuroscience, Centre for Developmental Neurobiology, King’s College London.

Marten Kehring
MD student
Robert Kilzer
MD student


Jana Zünkler
MD student
Mariam Hellmuth
MD Student


Francesca Kar Wey Lam
PhD Student